Change Research glomerular filtration rate in patients with primary hypertension

The study of 30 people with hypertension author Huynh Van Minh result 50% of patients with proteinuria appeared with many different levels. The level of average blood pressure of 166 / 97mmHg correlated with urinary albumin concentration was 71.9 mg / 24 h. Study of Chu Minh Ha in 05 years from 2001 to 2005 have 3306 patients hospitalized for hypertension in total 92 103 inpatient percentage of 3.6%. In hypertensive complications from kidney failure percentage is 5.9%.

In 1996 researchers working group, track 1795 hypertensive patients 10 years Buckalew author comments hypertensive renal function decline as rapidly. Rate and the higher the number, the time of progression to end-stage renal failure as quickly. The author also Ridao 2001 for similar results. The authors conclude that hypertension is one of the most important factors for kidney disease prognosis and treatment of hypertension decided to slow the progression of kidney failure.

  The study of 840 patients with hypertension and nephropathy, author Peterson commented hypertension treatment will prevent coils early kidney disease and hypertension. Treatment of hypertension decided to slow the progression of kidney failure. NHANES III study comparing over 15600 patients and MDRD study found that 40% of hypertension among glomerular filtration rate of 90 ml / min / 1,73m2 lower MDRD study. However, the blood pressure 160/100 mmHg on the same two studies: 20% of patients with glomerular filtration rate: 15-30 ml / min / 1,73m2 2 times higher than the glomerular filtration rate in the group of 30 ml / min / 1,73m2. Puttinger H. 2003, see Fraser 2013 hypertensive kidney disease is the main cause of end-stage renal failure. When kidney function is severely impaired control of blood pressure treatment and maintain kidney function very difficult. This study suggests that blood pressure control achieved the goal of helping patients reduce kidney damage as well as block in other target organs. Redon J. 2006 epidemiological study of the incidence of cardiovascular disease in patients with renal impairment. The authors concluded that in patients with hypertension, the prevalence of cardiovascular disease increased in the same direction with the severity of renal impairment. Glomerular filtration rate test to help predict cardiovascular patients with hypertension. The study's authors Pontremoli in Genoa, Italy in 459 diabetic patients with primary hypertension untreated. The research results show that the incidence of kidney damage is 24%, 12% and microalbuminuria was reduced creatinine clearance was 13%. The presence of kidney damage leading to cardiovascular abnormalities 3.3 times higher than people without kidney damage. If there is simultaneous decline in creatinine clearance and urinary albumin, up to 68% of patients with a high risk. In conclusion, the authors suggest that the role of assessment tests glomerular filtration rate and urinary microalbumin test is the simplest and most important to assess target organ damage in patients with primary hypertension.

Thus most of the studies showed decreased glomerular filtration rate with the increase in the number of both systolic blood pressure and diastolic. Glomerular filtration rate seems to decrease faster in people with hypertension systolic than diastolic hypertension. Time as long hypertension, the risk reduction in glomerular filtration rate increases. Glomerular filtration rate decreased faster in the elderly. And when the glomerular filtration rate decreased cardiovascular events also increased. Thus it can be said glomerular filtration rate is an independent risk factor for hypertension, although the decline in glomerular filtration rate due to hypertensive renal injury. Glomerular filtration rate in patients with kidney damage caused by hypertension or hypertension are due to improved blood pressure control achieved if the target figure. Glomerular filtration rate is stable if good treatment of urinary albumin levels.